Evaluation Strategy Establishing the type of LGMD can be useful in discussions of the clinical course of the disease and for genetic counseling purposes. Weakness in pelvic and shoulder muscles may occur later. This law also established the Muscular Dystrophy Coordinating Committee to help focus research efforts through a coherent research strategy. In some cases, a person with a muscle disease will get progressively weaker to the extent that it shortens lifespan due to heart and breathing complications. For example, immunostaining of muscle from individuals with pathogenic variants in the gene encoding alpha-sarcoglycan show marked deficiency or absence of alpha- beta- gamma- and delta-sarcoglycan.
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What are the symptoms of adult onset muscular dystrophy?
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